生物来源
rabbit
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, rat, mouse
制造商/商品名称
Chemicon®
技术
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... CASP1(834)
mouse ... Casp1(12362)
rat ... Casp1(25166)
一般描述
半胱天冬酶-1（ICE，白介素-1b转化酶）是哺乳动物的半胱天冬酶，负责将白介素-1b和IL-18的形式蛋白水解转化为活性细胞因子。 像其他半胱天冬酶一样，半胱天冬酶-1本身被合成为一种酶，在激活过程中被裂解为大（20 kDa）和小（10 kDa）亚基。
特异性
AB1871识别45 kDa procaspase-1和20 kDa裂解的半胱天冬酶-1。
应用
蛋白质印迹：1-4 μg/mL
免疫沉淀：4-8 μg/mL
免疫荧光：10-20 μg/mL
最佳工作稀释度必须由最终用户进行确定。
免疫沉淀：4-8 μg/mL
免疫荧光：10-20 μg/mL
最佳工作稀释度必须由最终用户进行确定。
该抗半胱天冬酶-1抗体经过验证可用在IF、IP、WB中检测半胱天冬酶-1。
外形
亲和纯化的免疫球蛋白。 在含有50%甘油、1％BSA和0.02%叠氮化钠的PBS（pH 7.2）中的溶液。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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WGK
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