产品名称
Anti-Neurotrophin 4/5 Antibody, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, monkey, human, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NTF4(4909)
Application
Anti-Neurotrophin 4/5 Antibody is an antibody against Neurotrophin 4/5 for use in ELISA, WB, IH.
Immunohistochemistry: 1-2 μg/mL (see suggested protocol).
Immunoblotting: 1-2 μg/mL
ELISA: 1-2 μg/mL
Inhibition of biological activity in vitro: 1-2 μg/mL.
BIOLOGICAL ACTIVITY: Neutralizes NT4, but not other neurotrophins.
In vivo animal studies: use neat
Optimal working dilutions must be determined by end user.
Immunoblotting: 1-2 μg/mL
ELISA: 1-2 μg/mL
Inhibition of biological activity in vitro: 1-2 μg/mL.
BIOLOGICAL ACTIVITY: Neutralizes NT4, but not other neurotrophins.
In vivo animal studies: use neat
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
Biochem/physiol Actions
Neurotrophin 4 (NT4). By dot blot, less than 1% cross-reactivity against NGF, BDNF or NT3.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Recombinant human Neurotrophin 4 (NT4).
Other Notes
Replaces: AB1455P
Physical form
Format: Purified
Purified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).
Preparation Note
Maintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
R Cabo et al.
Anatomical record (Hoboken, N.J. : 2007), 298(3), 624-629 (2014-09-19)
Some mechanoreceptors in mammals depend totally or in part on the neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4), and their receptor TrkB, for development and maintenance. These actions are presumably exerced regulating the survival of discrete sensory neurons in
Takahiro Ishimoto et al.
NPJ science of food, 8(1), 11-11 (2024-02-07)
Oral administration of the food-derived antioxidant amino acid ergothioneine (ERGO) results in its efficient distribution in the brain and enhances cognitive function. However, effect of ERGO deficiency on cognitive impairment and the underlying mechanisms remain unknown. We revealed that cognitive
Erica Hurtado et al.
Frontiers in molecular neuroscience, 10, 147-147 (2017-06-03)
The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system. The potentiation of acetylcholine (ACh) release by BDNF requires TrkB phosphorylation and Protein Kinase C (PKC) activation.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持