生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, human, mouse
种属反应性（根据同源性预测）
dog (based on 100% sequence homology)
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
dog ... Gjc1(490936)
human ... GJC1(10052)
mouse ... Gjc1(14615)
rat ... Gjc1(266706)
特异性
识别人类，大鼠和小鼠间隙连接蛋白45。由于序列同源性，该抗体也有望与犬间隙连接蛋白45（100%同源）发生反应。其他物种还未经测试。
免疫原
KLH偶联合成线性肽，对应于人间隙连接蛋白45的C末端附近区域。
应用
使用经验证可用于IP、WB、IH的细胞质抗间隙连接蛋白45抗体（近C端）检测间隙连接蛋白45。
外形
形式：纯化
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
M Nitta et al.
Journal of animal science, 88(10), 3269-3279 (2010-06-22)
During mammalian oogenesis, intercellular communication between oocytes and the surrounding follicle cells through gap junction channels is crucial for oocyte development and maturation. The channel properties of gap junctions may be affected by the composition or combination of connexins, the
Erika R Kinjo et al.
PloS one, 9(10), e109149-e109149 (2014-10-10)
Gap junction (GJ) channels have been recognized as an important mechanism for synchronizing neuronal networks. Herein, we investigated the participation of GJ channels in the pilocarpine-induced status epilepticus (SE) by analyzing electrophysiological activity following the blockade of connexins (Cx)-mediated communication.
Karen Maass et al.
Circulation research, 101(12), 1283-1291 (2007-10-13)
Haplodeficient mice expressing carboxyl-terminally truncated Cx43 (K258stop/KO), instead of the wild-type Cx43 isoform, reach adulthood and reveal no abnormalities in heart morphology. Here, we have analyzed the expression of K258stop protein and the morphology of gap junctions in adult hearts
Loïc Le Gal et al.
Journal of the American Heart Association, 8(8), e010823-e010823 (2019-04-05)
Background Gap junction channels made of Connexin37 (Cx37) are expressed by aortic endothelial and smooth muscle cells of hypertensive mice, as well as by the renin-secreting cells of kidneys. Methods and Results To decipher whether Cx37 has any role in
Junichi Sugita et al.
Nature communications, 12(1), 1910-1910 (2021-03-28)
Cardiac arrhythmias are a primary contributor to sudden cardiac death, a major unmet medical need. Because right ventricular (RV) dysfunction increases the risk for sudden cardiac death, we examined responses to RV stress in mice. Among immune cells accumulated in
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