推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
bovine, eukaryotes, human
制造商/商品名称
Chemicon®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... UBAP2(55833)
特异性
Ubiquitin (76 amino acid, 8.5 kDa). Shows staining of neurofibrillary tangles, neurites in senile plaques and a subset of neuronal processes. No reactivity seen to tau, neurofilament or microtubule-associated proteins.
免疫原
Purified uboquitin covalently coupled to KLH using glutaraldehde.
应用
Anti-Ubiquitin Antibody detects level of Ubiquitin & has been published & validated for use in WB, IH, IH(P).
Immunohistochemistry: 1:1,000-1:5,000. Tissue fixed in 10% formalin, Bouin′s fixative for 1-2 days and embedded in paraffin, or unfixed frozen tissues may be used.
Immunoblotting: 1:1,000-1:5,000.
Optimal working dilutions must be determined by end user.
Immunoblotting: 1:1,000-1:5,000.
Optimal working dilutions must be determined by end user.
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
Ubiquitin & Ubiquitin Metabolism
外形
Neat rabbit antisera with 10 mM sodium azide.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Nataša Bauer et al.
Frontiers in plant science, 10, 1469-1469 (2019-12-12)
MATH-BTB proteins are known to act as substrate-specific adaptors of CUL3-based E3 ligases in the ubiquitin proteasome pathway. Their BTB domain binds to CUL3 scaffold proteins and the less conserved MATH domain targets a highly diverse collection of substrate proteins
Evaluation of selected binding domains for the analysis of ubiquitinated proteomes.
Nakayasu, ES; Ansong, C; Brown, JN; Yang, F; Lopez-Ferrer, D; Qian, WJ; Smith, RD; Adkins, JN
Journal of the American Society For Mass Spectrometry null
Peter Sutovsky et al.
Reproduction (Cambridge, England), 129(3), 269-282 (2005-03-08)
Major vault protein (MVP), also called lung resistance-related protein is a ribonucleoprotein comprising a major part (>70%) of the vault particle. The function of vault particle is not known, although it appears to be involved in multi-drug resistance and cellular
Jackalina M Van Kampen
Methods in molecular biology (Clifton, N.J.), 1806, 255-267 (2018-06-30)
Progranulin (PGRN) is a multifunctional protein that is widely expressed throughout the brain, where it has been shown to be a critical regulator of CNS inflammation (Ahmed et al., J Neuroinflammation 4:7, 2007; Yin et al., J Exp Med 207:117-128
Ernesto S Nakayasu et al.
Journal of proteome research, 14(9), 4029-4038 (2015-07-07)
Ubiquitination is a key protein post-translational modification that regulates many important cellular pathways and whose levels are regulated by equilibrium between the activities of ubiquitin ligases and deubiquitinases. Here, we present a method to identify specific deubiquitinase substrates based on
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