AB1585
抗多巴胺β羟化酶抗体
serum, Chemicon®
别名:
DBH, Dopamine beta-monooxygenase
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
radioimmunoassay
western blot
radioimmunoassay
western blot
Species reactivity:
bovine, guinea pig, rat, human, feline, rabbit
Citations:
36
Technique(s):
immunohistochemistry: suitable
radioimmunoassay: suitable
western blot: suitable
radioimmunoassay: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗多巴胺β羟化酶抗体, serum, Chemicon®
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
bovine, guinea pig, rat, human, feline, rabbit
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
radioimmunoassay: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... DBH(1621)
Analysis Note
对照
大脑（纹状体/黑质）
大脑（纹状体/黑质）
Application
使用经验证可用于IH、FUNC、RIA & Wb的抗多巴胺 β 羟化酶抗体检测多巴胺 β 羟化酶。
免疫组化：1:2,000，使用ABC检测方法对兔子和豚鼠进行。
蛋白质印迹法
RIA
抑制体内和体外研究。
最佳工作稀释度必须由最终用户进行确定。
蛋白质印迹法
RIA
抑制体内和体外研究。
最佳工作稀释度必须由最终用户进行确定。
研究子类别
神经递质 & 受体
神经元 & 胶质标记
神经递质 & 受体
神经元 & 胶质标记
研究类别
神经科学
神经科学
Biochem/physiol Actions
识别多巴胺β羟化酶。AB1585在牛肾上腺匀浆的蛋白质印迹上与单条带反应，仅染色已知含有DBH的细胞，例如交感神经元，肾上腺髓质细胞和中枢肾上腺素能神经元。通过与酶预温育消除染色。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
69 kDa
Immunogen
来自牛肾上腺的天然酶。
Other Notes
替代品：AB145
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
兔血清。 冻干，不含防腐剂。用50 μL无菌蒸馏水复溶。离心以除去任何不溶物。
未纯化
Preparation Note
自收到之日起，冻干材料在-20至-70°C下可保存长达12个月。复溶后，以未稀释等分试样的形式在-20至-70°C下保存长达6个月。应避免反复冻/融循环。甘油可按1:1加入，以增加稳定性。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Directed differentiation of neural cells to hypothalamic dopaminergic neurons.
Ohyama, K; Ellis, P; Kimura, S; Placzek, M
Development null
Jian Qi et al.
PloS one, 6(8), e23275-e23275 (2011-08-23)
The synaptic connections between neurokinin 1 (NK1) receptor-like immunoreactive (LI) neurons and γ-aminobutyric acid (GABA)-, glycine (Gly)-, serotonin (5-HT)- or dopamine-β-hydroxylase (DBH, a specific marker for norepinephrinergic neuronal structures)-LI axon terminals in the rat medullary dorsal horn (MDH) were examined
Jimena Baleriola et al.
Scientific reports, 6, 25928-25928 (2016-05-14)
Programmed cell death occurs naturally at different stages of neural development, including neurogenesis. The functional role of this early phase of neural cell death, which affects recently differentiated neurons among other cell types, remains undefined. Some mouse models defective in
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons.
Hook, V; Brennand, KJ; Kim, Y; Toneff, T; Funkelstein, L; Lee, KC; Ziegler, M; Gage, FH
Stem Cell Reports null
Junchao Tong et al.
Journal of neurochemistry, 102(5), 1691-1702 (2007-05-09)
We recently identified a noradrenaline-rich caudomedial subdivision of the human nucleus accumbens (NACS), implying a special function for noradrenaline in this basal forebrain area involved in motivation and reward. To establish whether the NACS, as would be expected, contains similarly
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