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主要文件

AB15794

Sigma-Aldrich

抗-Dexras1抗体

Chemicon®, from rabbit

别名:

Activator of G-Protein Signaling 1, AGS1

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

mouse

种属反应性(根据同源性预测)

rat (100% immunogen homology), human (100% immunogen homology)

制造商/商品名称

Chemicon®

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... RASD1(51655)

一般描述

Dexras1是Ras-G-蛋白超家族的成员,直接与Gialpha异源三聚体G蛋白结合,它似乎促进Gialpha上的鸟嘌呤核苷酸交换。Dexras1通过一氧化氮合酶参与NMDA受体信号传导。

特异性

Dexras1(G蛋白信号传导激活剂1,AGS1)。抗体通过蛋白质印迹识别小鼠脑提取物的~33 kDa的条带。该抗体还被用于检测棕色脂肪细胞裂解液中的Dexras1。
其他物种尚未经过测试

免疫原

合成肽。

应用

研究子类别
信号神经科学
研究类别
神经科学
蛋白质印迹:1:1,000,小鼠脑提取物中。
最佳工作稀释度必须由最终用户进行确定。
该抗Dexras1抗体经过验证可用于WB中,以用于检测Dexras1。

外形

免疫亲和纯化
溶于PBS中的液体。不含防腐剂

储存及稳定性

自发货之日起可在-70°C保存6个月

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Yu Zhang et al.
Aging cell, 17(3), e12754-e12754 (2018-03-27)
In neurons, increased protein-protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy-terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of Alzheimer's
Marek Lenarczyk et al.
Journal of molecular histology, 46(2), 123-136 (2014-12-24)
Activators of G-protein Signaling (AGS) are a family of accessory proteins that were discovered as modulators of heterotrimeric G-protein subunits. The primary aim of the present study was to localize Group I and II AGS proteins and determine the renal
Sudhir G Tattikota et al.
Molecular & cellular proteomics : MCP, 12(5), 1214-1225 (2013-01-30)
Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant
Li-Juan Zhu et al.
Journal of neurochemistry, 146(5), 598-612 (2018-06-03)
Anxiety disorders are associated with a high social burden worldwide. Recently, increasing evidence suggests that nuclear factor kappa B (NF-κB) has significant implications for psychiatric diseases, including anxiety and depressive disorders. However, the molecular mechanisms underlying the role of NF-κB
Sudhir G Tattikota et al.
Cell metabolism, 19(1), 122-134 (2013-12-24)
Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in

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