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AB15794

Sigma-Aldrich

抗-Dexras1抗体

Chemicon®, from rabbit

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别名:
Activator of G-Protein Signaling 1, AGS1
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

mouse

种属反应性(根据同源性预测)

rat (100% immunogen homology), human (100% immunogen homology)

制造商/商品名称

Chemicon®

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... RASD1(51655)

一般描述

Dexras1是Ras-G-蛋白超家族的成员,直接与Gialpha异源三聚体G蛋白结合,它似乎促进Gialpha上的鸟嘌呤核苷酸交换。Dexras1通过一氧化氮合酶参与NMDA受体信号传导。

特异性

Dexras1(G蛋白信号传导激活剂1,AGS1)。抗体通过蛋白质印迹识别小鼠脑提取物的~33 kDa的条带。该抗体还被用于检测棕色脂肪细胞裂解液中的Dexras1。
其他物种尚未经过测试

免疫原

合成肽。

应用

研究子类别
信号神经科学
研究类别
神经科学
蛋白质印迹:1:1,000,小鼠脑提取物中。
最佳工作稀释度必须由最终用户进行确定。
该抗Dexras1抗体经过验证可用于WB中,以用于检测Dexras1。

外形

免疫亲和纯化
溶于PBS中的液体。不含防腐剂

储存及稳定性

自发货之日起可在-70°C保存6个月

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Marek Lenarczyk et al.
Journal of molecular histology, 46(2), 123-136 (2014-12-24)
Activators of G-protein Signaling (AGS) are a family of accessory proteins that were discovered as modulators of heterotrimeric G-protein subunits. The primary aim of the present study was to localize Group I and II AGS proteins and determine the renal
Yu Zhang et al.
Aging cell, 17(3), e12754-e12754 (2018-03-27)
In neurons, increased protein-protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy-terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of Alzheimer's
Sudhir G Tattikota et al.
Molecular & cellular proteomics : MCP, 12(5), 1214-1225 (2013-01-30)
Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant
Li-Juan Zhu et al.
Journal of neurochemistry, 146(5), 598-612 (2018-06-03)
Anxiety disorders are associated with a high social burden worldwide. Recently, increasing evidence suggests that nuclear factor kappa B (NF-κB) has significant implications for psychiatric diseases, including anxiety and depressive disorders. However, the molecular mechanisms underlying the role of NF-κB
Sudhir G Tattikota et al.
Cell metabolism, 19(1), 122-134 (2013-12-24)
Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in

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