推荐产品
生物来源
rabbit
质量水平
偶联物
ALEXA FLUOR™ 488
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, mouse
种属反应性(根据同源性预测)
human (based on 100% sequence homology)
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... TUBB3(10381)
mouse ... Tubb3(22152)
rat ... Tubb3(246118)
一般描述
微管蛋白是小球状蛋白家族的几个成员之一,这些蛋白聚合形成称为微管的细胞骨架结构。微管蛋白家族中最常见的成员是α-微管蛋白和β-微管蛋白。通常由α-和β-微管蛋白亚基组成的微管蛋白二聚体组装到形成大聚合物的微管上。β-III微管蛋白是一种独特的微管亚基,几乎只在神经元中表达。由于β-III微管蛋白的独特表达模式,它通常被用作标记物,以从不表达它的其他脑细胞(例如神经胶质)中识别神经元细胞。β-III微管蛋白也可作为细胞结构标记,因为它主要存在于神经突延伸内。
特异性
该抗体可识别βIII微管蛋白。
免疫原
对应于人βIII微管蛋白的合成线性肽。
应用
免疫组化:代表性皮层已显示在成年小鼠大脑中起作用。
研究子类别
神经丝&神经元代谢
神经丝&神经元代谢
研究类别
神经科学
神经科学
质量
已通过免疫细胞化学在大鼠E18皮层细胞中进行评估。
免疫细胞化学分析:该抗体的1:400稀释液在大鼠E18皮质细胞中检测到βIII微管蛋白。
免疫细胞化学分析:该抗体的1:400稀释液在大鼠E18皮质细胞中检测到βIII微管蛋白。
目标描述
计算分子量为50 kDa
外形
亲和纯化
纯化的兔多克隆抗体与含0.1%叠氮化钠和15 mg/ml BSA的PBS中的Alexa Fluor™ 488偶联。
储存及稳定性
自发运之日起,在 2-8°C 条件下可稳定保存1年
分析说明
对照
大鼠E18皮层细胞
大鼠E18皮层细胞
法律信息
ALEXA FLUOR is a trademark of Life Technologies
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Emily R Aurand et al.
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Hydrogels provide a unique tool for neural tissue engineering. These materials can be customized for certain functions, i.e. to provide cell/drug delivery or act as a physical scaffold. Unfortunately, hydrogel complexities can negatively impact their biocompatibility, resulting in unintended consequences.
Zhenzhen Zhang et al.
Molecular vision, 24, 274-285 (2018-04-13)
To investigate the effect and mechanism of proresolving lipid mediator resolvin D1 (RvD1) on the corneal epithelium and the restoration of mechanical sensation in diabetic mice. Type 1 diabetes was induced in mice with intraperitoneal streptozocin injections. The healthy and
Yuan Zhang et al.
Frontiers in molecular biosciences, 8, 737472-737472 (2021-09-14)
Diabetes mellitus (DM) is a complex metabolic disorder. Long-term hyperglycemia may induce diabetic keratopathy (DK), which is mainly characterized by delayed corneal epithelial regeneration. MicroRNAs (miRNAs) have been reported to play regulatory roles during tissue regeneration. However, the molecular mechanism
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Mengliang Wu et al.
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Corneal immune cells interact with corneal sensory nerves during both homeostasis and inflammation. This study sought to evaluate temporal changes to corneal immune cell density in a mouse model of epithelial abrasion and nerve injury, and to investigate the immunomodulatory
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The primary aim of the present study was to examine the effects of microRNA‑21 (miR‑21) on the proliferation and differentiation of rat primary neural stem cells (NSCs) in vitro. miR‑21 was overexpressed in NSCs by transfection with a miR‑21 mimic. The
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