AB15014
Anti-Glycine Receptor α3 subunit Antibody
Chemicon®, from rabbit
别名:
glycine receptor alpha 3 subunit, glycine receptor, alpha 3, glycine receptor, alpha-3 polypeptide, ligand gated ion channel
登录 查看组织和合同定价。
选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
mouse, human
Citations:
2
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-Glycine Receptor α3 subunit Antibody, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GLRA3(8001)
Application
Anti-Glycine Receptor α3 subunit Antibody detects level of Glycine Receptor α3 subunit & has been published & validated for use in IH & WB.
Immunohistochemistry Analysis: 1:100-500 dilution from a previous lot detected Glycine Receptor α3 subunit in mouse spinal cord and mouse eye tissue.
Biochem/physiol Actions
Rat (92%) homology.
This antibody recognizes Glycine Receptor α3 subunit.
General description
Approx. 48 kDa
Glycine receptor α3 subunit, also known as GLRA3, belongs to the ligand-gated ion channel family. Glycine functions as a inhibitory neurotransmitter throughout the CNS of mammals. The Glycine receptor is a neurotransmitter ligand-gated ion channel. GLRA3 is a pentamer that is composed of ligand binding alpha and structural beta subunits. When glycine binds to the receptor, chloride conductance increases which produces hyperpolarization. It is expressed in the hippocampus, olfactory bulb, and cerebellum. GLRA3 may be involved in human and murine neurological disorders.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated linear peptide selected from residues surrounding the C-terminus of human Glycine Receptor α3 subunit.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate.
Kuhse, et al.
International Journal of Molecular Sciences, 24 (2023)
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain.
Mario A Acuña et al.
The Journal of clinical investigation, 126(7), 2547-2560 (2016-06-09)
Diminished inhibitory neurotransmission in the superficial dorsal horn of the spinal cord is thought to contribute to chronic pain. In inflammatory pain, reductions in synaptic inhibition occur partially through prostaglandin E2- (PGE2-) and PKA-dependent phosphorylation of a specific subtype of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持