产品名称
Anti-Corticosterone Antibody, serum, Chemicon®
biological source
sheep
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
radioimmunoassay: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Application
Anti-Corticosterone Antibody is an antibody against Corticosterone for use in ELISA, RIA.
ELISA: 1:200,000 (Sensitivity 5 pg/well, id-50 is 50 pg/well.)
RIA: 1:60,000 (Sensitivity 10 pg/tube, 50% displacement 60 pg/tube separating free and bound using ammonium sulfate 10 50% saturation.)
Optimal working dilutions must be determined by end user.
RIA: 1:60,000 (Sensitivity 10 pg/tube, 50% displacement 60 pg/tube separating free and bound using ammonium sulfate 10 50% saturation.)
Optimal working dilutions must be determined by end user.
Research Category
Metabolism
Metabolism
Research Sub Category
Metabolic Hormones & Receptors
Metabolic Hormones & Receptors
Biochem/physiol Actions
Corticosterone
Cross-reactivity: 11-dehydrocorticosterone 0.67%, Deoxycorticosterone 1.5%, 18-OH-DOC <0.01%, Cortisone <0.01%, Cortisol <0.01% and Aldosterone 0.2% by RIA.
Cross-reactivity: 11-dehydrocorticosterone 0.35%, Progesterone 0.004%, 18-OH-DOC 0.01%, Cortisol 0.12%, 18-OH-B 0.02% and Aldosterone 0.06% by ELISA.
Cross-reactivity: 11-dehydrocorticosterone 0.67%, Deoxycorticosterone 1.5%, 18-OH-DOC <0.01%, Cortisone <0.01%, Cortisol <0.01% and Aldosterone 0.2% by RIA.
Cross-reactivity: 11-dehydrocorticosterone 0.35%, Progesterone 0.004%, 18-OH-DOC 0.01%, Cortisol 0.12%, 18-OH-B 0.02% and Aldosterone 0.06% by ELISA.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Corticosterone-3-cmo-urease
Physical form
Sheep serum. Liquid in 0.1% sodium azide.
Preparation Note
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
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Scientific reports, 9(1), 14018-14018 (2019-10-02)
Corticosteroid-binding globulin (CBG) is synthesized by the liver and secreted into the bloodstream where binds to glucocorticoids. Thus CBG has the role of glucocorticoid transport and free hormone control. In addition, CBG has been detected in some extrahepatic tissues without
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Endocrinology, 157(8), 3253-3265 (2016-06-21)
Hypothalamic-pituitary-thyroid (HPT) axis activity is important for energy homeostasis, and is modified by stress. Maternal separation (MS) alters the stress response and predisposes to metabolic disturbances in the adult. We therefore studied the effect of MS on adult HPT axis
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