产品名称
抗单羧酸转运蛋白1抗体, from chicken, purified by affinity chromatography
biological source
chicken
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
species reactivity (predicted by homology)
mouse (immunogen homology)
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
isotype
IgY
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Analysis Note
对照
大鼠脑膜组织裂解液
大鼠脑膜组织裂解液
通过蛋白质印迹对大鼠脑膜组织裂解液进行了评估。
蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg大鼠脑膜组织裂解液中检测到大鼠脑膜组织裂解液。
蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg大鼠脑膜组织裂解液中检测到大鼠脑膜组织裂解液。
Application
免疫组化分析：代表批次的1：2,500稀释液可检测大鼠骨骼肌和大鼠肾皮质组织。
抗单羧酸盐转运蛋白1抗体是一种高度特异性的鸡多克隆抗体，靶向MCT1，& 已在蛋白质印迹 & IHC（石蜡）中进行了测试。
研究子类别
信号神经科学
信号神经科学
研究类别
神经科学
神经科学
Biochem/physiol Actions
该抗体可识别单羧酸转运蛋白1的C端。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
单羧酸转运蛋白1（MCT1），也称为溶质载体家族16成员1（SLC16A1），催化许多单羧酸盐在质膜上的快速转运，例如乳酸盐，丙酮酸盐，衍生自亮氨酸，缬氨酸和异亮氨酸的支链含氧酸，以及酮体乙酰乙酸盐，β-羟基丁酸酯和乙酸盐。单羧酸转运蛋白1位于细胞膜上，在正常和癌症细胞中均有广泛表达。单羧酸转运蛋白1参与乳酸盐转运（SDLT）的症状性缺乏。
在~44 kDa和~55 kDa处观察到条带。在~47 kDa处观察到该蛋白（Sepponen, K., et al. (2003).Acta Physiol Scand.177(1):79-86.）。此外，在某些细胞裂解液中，在~55 kDa处观察到这种蛋白，但在瘤胃中，在~47 kDa和~55 kDa处出现两个不同的条带除外（Koho, N., et al. (2005).Comp Biochem Physiol A Mol Integr Physiol.141(1):29-34.）。已知其也被糖基化（Carpenter, L., et al. (1996).Biochim Biophys Acta.1279(2):157-163）。
Immunogen
对应于大鼠单羧酸转运蛋白1的C端的KLH偶联线性肽。
表位：C端
Other Notes
替代品：AB1286
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
亲和纯化
纯化的鸡多克隆IgY溶于含0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。
Preparation Note
自发运之日起，在 2-8°C 条件下可稳定保存1年
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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