推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
rat ... Cyp3A23-3A1(25642)
特异性
Reacts with rat cytochrome P450 enzyme CYP3A1 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes including CYP3A2.
免疫原
Synthetic peptide
应用
Research Category
Metabolism
Metabolism
Research Sub Category
Enzymes & Biochemistry
Enzymes & Biochemistry
This Anti-Cytochrome P450 Enzyme CYP3A1 Antibody is validated for use in IH, WB for the detection of Cytochrome P450 Enzyme CYP3A1.
Western blot
Immunohistochemistry on formaldehyde treated sections.
Optimal working dilutions must be determined by end user.
Immunohistochemistry on formaldehyde treated sections.
Optimal working dilutions must be determined by end user.
外形
Rabbit antiserum. Liquid. Contains no preservative.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Marta Rysz et al.
The Journal of pharmacology and experimental therapeutics, 389(1), 87-95 (2024-03-07)
The organic anion transporting polypeptide (OATP)2B1 [(gene: solute carrier organic anion transporter family member 2B1 (SLCO2B1)] is an uptake transporter that facilitates cellular accumulation of its substrates. Comparison of SLCO2B1+/+ knockin and rSlco2b1-/- knockout rats showed a higher expression of
Sofia Cussotto et al.
EBioMedicine, 66, 103307-103307 (2021-04-06)
The role of the gut microbiome in the biotransformation of drugs has recently come under scrutiny. It remains unclear whether the gut microbiome directly influences the extent of drug absorbed after oral administration and thus potentially alters clinical pharmacokinetics. In
James R Reed et al.
Drug metabolism and disposition: the biological fate of chemicals, 51(9), 1196-1206 (2023-06-23)
Liver cytochrome P450s (CYPs) of the endoplasmic reticulum (ER) are involved in the metabolism of exogenous and endogenous chemicals. The ER is not uniform, but possesses ordered lipid microdomains containing higher levels of saturated fatty acids, sphingomyelin, and cholesterol and
Masami Doi et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(5), 506-514 (2019-08-14)
The inductive effects of dexamethasone on hepatic midazolam metabolism were examined in Wistar rats with acute renal failure (ARF) to clarify whether the ARF-related decrease in the hepatic expression of drug-metabolizing enzymes is caused by an impairment in the translation/polypeptide
Philip Martin et al.
Acta pharmacologica Sinica, 31(1), 51-65 (2010-01-06)
The aim of this study was to investigate the impact on expression of mRNA and protein by paradigm inducers/activators of nuclear receptors and their target genes in rat hepatic and intestinal cells. Furthermore, assess marked inter laboratory conflicting reports regarding
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