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Merck
CN
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文件

AB10522

Sigma-Aldrich

Anti-Neuropilin-2 Antibody

serum, from rabbit

别名:

Vascular endothelial cell growth factor 165 receptor 2, neuropilin 2, receptor for VEGF165 and semaphorins class 3, vascular endothelial growth factor-165 receptor 2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

100

抗体形式

serum

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

mouse

技术

immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG

NCBI登记号

NP_110496.1

UniProt登记号

O35276

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... NRP2(8828)

一般描述

There are two forms of Neuropilin: Neuropilin-1 and Neuropilin-2. These are non–tyrosine kinase receptors that bind to VEGF and semaphorins (SEMA3A, SEMA3B, and SEMA3F) and play an important role in the critical functioning of the nervous system. Neuropilin-2 is expressed in tumor cells, and mature and developing endothelial cells and vascular smooth muscle cells. This expression has been associated with tumor angiogenesis and progression.

特异性

This antibody recognizes Neuropilin-2.

免疫原

His-tagged partial recombinant rat Neuropilin-2 protein.

应用

Detect Neuropilin-2 using this Anti-Neuropilin-2 Antibody validated for use in WB, IH, IP & IF.

质量

Evaluated by Western Blot in mouse P1 brain tissue lysate.

Western Blot Analysis: 1:1000 dilution of this antibody detected Neuropilin-2 on 10 µg of mouse P1 brain tissue lysate.

目标描述

130 kDa

联系

Replaces: AB9160

外形

Unpurified Rabbit Serum containing 0.05% Sodium Azide.

分析说明

Control
Mouse P1 brain tissue lysate

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

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Saravana K Ramasamy et al.
Nature, 507(7492), 376-380 (2014-03-22)
Blood vessel growth in the skeletal system and osteogenesis seem to be coupled, suggesting the existence of molecular crosstalk between endothelial and osteoblastic cells. Understanding the nature of the mechanisms linking angiogenesis and bone formation should be of great relevance
Ryosuke Tsuchimochi et al.
Stem cell reports, 18(4), 899-914 (2023-03-25)
Cell replacement therapy is expected as a new and more radical treatment against brain damage. We previously reported that transplanted human cerebral organoids extend their axons along the corticospinal tract in rodent brains. The axons reached the spinal cord but

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