AB10516
抗血管生成素-1抗体
from rabbit
别名:
Hepatic fibrinogen/angiopoietin-related protein, PPARG angiopoietin related protein, angiopoietin-like 4, angiopoietin-like 4 protein, angiopoietin-related protein 4, fasting-induced adipose factor, hepatic angiopoietin-related protein, peroxisome prolif
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所有图片(1)
About This Item
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
horse (95% sequence homology), dog (95% sequence homology), mouse (100% sequence homology), rat (95% sequence homology), bovine (95% sequence homology), mouse, human (90% sequence homology), pig (95% sequence homology)
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
一般描述
哺乳动物原始脉管系统的重塑以形成成熟的心血管系统包括许多指导内皮细胞发育的因素。血管生成素-1是一种与内皮特异性Tie-2受体相互作用的血管生成分泌型蛋白。它主要在发育中的内皮细胞中表达。在胚胎发育过程中，Ang-1结合并诱导Tie-2的酪氨酸磷酸化。Ang-1似乎在介导基质和间充质中起关键作用。它介导血管成熟和稳定。Ang-1可能在心脏发育中起关键作用。Ang-1缺陷小鼠模仿Tie-2缺陷动物表现出的表型。Ang-1的同系物，称为血管生成素-2，可以作为Ang-1和Tie-2的拮抗剂。Ang-1和Ang-2具有约60%的序列同源性。
特异性
该抗体可识别血管生成素-1。
免疫原
该抗体是从用选自小鼠血管生成素-1的KLH偶联合成肽免疫的兔中产生的。
应用
抗血管生成素-1抗体是针对血管生成素-1的抗体，可用于WB。
质量
通过蛋白质印迹在小鼠肾裂解液中进行了评估。
蛋白质印迹分析：： 该批次的1：1,000稀释液在10 µg小鼠肾裂解液中检测到血管生成素-1。
蛋白质印迹分析：： 该批次的1：1,000稀释液在10 µg小鼠肾裂解液中检测到血管生成素-1。
目标描述
57 kDa
外形
形式：纯化
分析说明
对照
小鼠肾裂解液
小鼠肾裂解液
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Yu Zhan et al.
Frontiers in neuroscience, 13, 701-701 (2019-07-30)
Xiaoshuan enteric-coated capsule (XSEC) is a Chinese medicinal compound widely used for treatment of ischemic cerebrovascular diseases. Enriched environment (EE) is an effective rehabilitative protocol designed to enhance sensorimotor, cognitive and social stimulation. This study aimed to apply magnetic resonance
Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes.
Feng, et al.
Frontiers in Cellular Neuroscience, 17, 1125412-1125412 (2023)
Mansoor Syed et al.
Nature communications, 8(1), 1173-1173 (2017-10-29)
Hyperoxia-induced acute lung injury (HALI) is a key contributor to the pathogenesis of bronchopulmonary dysplasia (BPD) in neonates, for which no specific preventive or therapeutic agent is available. Here we show that lung micro-RNA (miR)-34a levels are significantly increased in
Angara Sureshbabu et al.
Respiratory research, 16, 4-4 (2015-01-17)
Earlier studies have reported that transforming growth factor beta 1(TGFβ1) is a critical mediator of hyperoxia-induced acute lung injury (HALI) in developing lungs, leading to impaired alveolarization and a pulmonary phenotype of bronchopulmonary dysplasia (BPD). However, the mechanisms responsible for
Defang Pang et al.
Experimental & molecular medicine, 50(9), 117-117 (2018-09-07)
We have previously demonstrated that in response to cerebral ischemia (CI), the growth factor angiopoietin-1 (Ang1) and α5β1 integrin are both induced in cerebral vessels, which likely provide positive signals driving the endogenous angiogenic response and vascular protection after CI.
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