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一般描述
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.
特异性
Other species have not been tested.
The antibody reacts with the 29 kDa KLK3 antigen.
免疫原
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.
应用
This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).
质量
Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.
目标描述
~31 kDa observed.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
外形
Saturated Ammonium Sulfate (SAS)
Format: Purified
储存及稳定性
Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°
分析说明
Control
Western Blot : Mouse brain lysate.
Western Blot : Mouse brain lysate.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Ana M Blázquez-Medela et al.
Medicine, 94(41), e1617-e1617 (2015-10-16)
Early detection of hypertensive end-organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients suffering from arterial hypertension. Presently, there are no biomarkers for the detection of hypertensive target organ damage, most outstandingly including blood vessels, the
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