推荐产品
生物来源
rabbit
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, human, rat
制造商/商品名称
Chemicon®
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Sod2(20656)
一般描述
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
免疫原
Epitope: AA G93 – Y217
Recombinant human SOD2
应用
This Anti-SOD2 Antibody is validated for use in WB for the detection of SOD2.
质量
Routinely evaluated by immunoblot.
目标描述
28 kDa
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Yukio Shimasaki et al.
Circulation research, 113(7), 891-901 (2013-07-04)
Mitochondria, although required for cellular ATP production, are also known to have other important functions that may include modulating cellular responses to environmental stimuli. However, the mechanisms whereby mitochondria impact cellular phenotype are not yet clear. To determine how mitochondria
Anthony R Cyr et al.
Redox biology, 1, 172-177 (2013-09-12)
Manganese superoxide dismutase, encoded by the Sod2 gene, is a ubiquitously expressed mitochondrial antioxidant enzyme that is essential for mammalian life. Mice born with constitutive genetic knockout of Sod2 do not survive the neonatal stage, which renders the longitudinal study
Loss of LRPPRC causes ATP synthase deficiency.
Mourier, A; Ruzzenente, B; Brandt, T; Kuhlbrandt, W; Larsson, NG
Human Molecular Genetics null
Thomas Rostgaard Andersen et al.
PloS one, 11(2), e0148236-e0148236 (2016-02-18)
The effects of 52 weeks of soccer or resistance training were investigated in untrained elderly men. The subjects aged 68.1±2.1 yrs were randomised into a soccer (SG; n = 9), a resistance (RG; n = 9) and a control group
Xiaoyuan Lin et al.
Aging and disease, 13(5), 1471-1487 (2022-10-04)
Excessive sodium fluoride (NaF) intake interferes with reproductive function in humans and animals; however, strategies to prevent these effects are still underexplored. Here, we showed that in vivo and in vitro supplementation of folic acid (FA) efficaciously improved the quality
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