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安全信息

8.55140

Sigma-Aldrich

Fmoc-PAL-Linker

Novabiochem®

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别名:
Fmoc-PAL-Linker
经验公式(希尔记法):
C29H31NO7
分子量:
505.56
UNSPSC代码:
12352209
NACRES:
NA.22

质量水平

产品线

Novabiochem®

形式

solid

反应适用性

reagent type: linker

制造商/商品名称

Novabiochem®

mp

178-180 °C

应用

peptide synthesis

官能团

Fmoc

储存温度

2-8°C

InChI

1S/C29H31NO7/c1-34-26-15-19(36-14-8-7-13-28(31)32)16-27(35-2)24(26)17-30-29(33)37-18-25-22-11-5-3-9-20(22)21-10-4-6-12-23(21)25/h3-6,9-12,15-16,25H,7-8,13-14,17-18H2,1-2H3,(H,30,33)(H,31,32)

InChI key

ATYUCXIJDKHOPX-UHFFFAOYSA-N

一般描述

Barany′s aminomethyl-dimethoxyphenoxyvaleric acid linker [1]. The amino group of this linker can be easily acylated under standard coupling conditions. Following peptide assembly, treatment with 95% TFA containing scavengers releases the desired peptide amide. Studies have shown the acid sensitivity of this linker to be around twice that of the Rink amide linker [2]. There is some evidence to suggest that PAL resins give greater yields in microwave assisted synthesis.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

分析说明

Color (visual): white to beige to grey
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(0811)): ≥ 98.0 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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