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Merck
CN
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安全信息

8.55053

Sigma-Aldrich

Dnp NovaTag® resin

Novabiochem®

别名:

N-Dnp-NÆ-Fmoc-ethylenediamine MPB-AM resin

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About This Item

质量水平

产品线

NovaSyn® TG
Novabiochem®

形式

beads

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

amine

储存温度

15-25°C

一般描述

Dnp NovaTag resin is an ideal tool for the synthesis of FRET peptide substrates based on the 7-methoxycoumarin (Mca) and 2,4-dintrophenyl (Dnp) fluorophore/quench pair. The resin pre-loaded with the Dnp quencher group can be used directly in Fmoc SPPS. Following peptide assembly, the Mca group is coupled to the N-terminal N-amino group using Mca-OSu, or introduced to a side-chain of Lys using Fmoc-Lys(Mca)-OH, to give after TFA cleavage the desired FRET peptide substrate.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

联系

Replaces: 04-12-3903

分析说明

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 % DVB 100 - 200 mesh

法律信息

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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