产品名称
Dansyl NovaTag® resin, Novabiochem®
product line
NovaSyn® TG
Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
15-25°C
Quality Level
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 & DVB 100 - 200 mesh
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 & DVB 100 - 200 mesh
General description
Dansyl NovaTag resin is an ideal tool for the synthesis of Dansyl-labeled peptides. The resin pre-loaded with the Dansyl chromophore can be used directly in Fmoc SPPS. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the Dansyl-labeled peptide. This resin has been recently used to dansyl-labeled amyloid-RGD peptides [1] and FRET probes for mercury binding protein MerP [2].
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] S. L. Gras, et al. (2008) Biomaterials, 29, 1553.
[2] B. R. White, et al. (2008) Analyst,, 133, 65
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] S. L. Gras, et al. (2008) Biomaterials, 29, 1553.
[2] B. R. White, et al. (2008) Analyst,, 133, 65
Other Notes
Replaces: 04-12-3900
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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