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Merck
CN
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安全信息

8.53029

Sigma-Aldrich

Boc-Glu(OcHx)-OH

Novabiochem®

别名:

Boc-Glu(OcHx)-OH, N-α-t.-Boc-L-glutamic acid γ-cyclohexyl ester

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About This Item

经验公式(希尔记法):
C16H27NO6
CAS号:
分子量:
329.39
UNSPSC代码:
12352209
NACRES:
NA.22

质量水平

产品线

Novabiochem®

检测方案

≥98% (TLC)

形式

powder

反应适用性

reaction type: Boc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

mp

54-57 °C

应用

peptide synthesis

官能团

carboxylic acid

储存温度

2-30°C

InChI

1S/C16H27NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-10-13(18)22-11-7-5-4-6-8-11/h11-12H,4-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1

InChI key

FDNMLANBNJDIRG-LBPRGKRZSA-N

一般描述

Standard building block for introduction of glutamic acid in Boc SPPS. This side-chain protecting group for glutamic acid is used to minimize side reactions during acidic and basic treatments [1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

[1] J. P. Tam, et al. (1979) Tetrahedron Lett., 42, 4033.

联系

Replaces: 04-12-0121

分析说明

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -9.0 - -7.0 °
Purity (TLC(0811)): ≥ 98 %
Purity (DC (0157)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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实验方案

Anhydrous HF is the preferred reagent for peptide cleavage from Boc-based resins, versatile and effective for various peptide synthesis.

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