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Merck
CN

8.53008

Boc-His(Dnp)-OH isopropanol

Novabiochem®

别名:

Boc-His(Dnp)-OH isopropanol, N-α-t.-Boc-N-im-dinitrophenyl-L-histidine isopropanol

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关于此项目

经验公式(希尔记法):
C17H19N5O8 · xC3H8O
分子量:
421.36
NACRES:
NA.22
UNSPSC Code:
12352209
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产品名称

Boc-His(Dnp)-OH isopropanol, Novabiochem®

product line

Novabiochem®

assay

≥98% (TLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

15-25°C

Quality Level

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in EtOAc): +52.5 - +59.5 °
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clear soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

General description

Standard building block for introduction of histidine amino-acid residues by Boc SPPS. The Dnp group is stable to HF and TFMSA. Normally removed with thiophenol prior to HF treatment.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Other Notes

Replaces: 04-12-0023

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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实验方案

Anhydrous HF is the preferred reagent for peptide cleavage from Boc-based resins, versatile and effective for various peptide synthesis.

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