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8.52352

(2S,3S)-Fmoc-Abu(3-N3)-OH

Name: (2S,3S)-Fmoc-Abu(3-N3)-OH
Brand: MM

Novabiochem^®

别名:

(2S,3S)-Fmoc-Abu(3-N3)-OH, (2S,3S)-2-(Fmoc-amino)-3-azidobutanoic acid

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About This Item

经验公式（希尔记法）:

C₁₉H₁₈N₄O₄

CAS号:

131669-42-6

分子量:

366.37

UNSPSC代码:

12352209

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此商品	MAK266	MAK270	MAK215
MAK264 高灵敏度甘油三酯检测试剂盒（荧光法）	MAK266 甘油三酯定量检测试剂盒（比色法/荧光法）	MAK270 高灵敏度游离甘油荧光法检测试剂盒	MAK215 高灵敏度脂解检测试剂盒
detection method fluorometric	detection method colorimetric, fluorometric	detection method fluorometric	detection method fluorometric
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
application(s) cosmetics food and beverages	application(s) -	application(s) cosmetics environmental food and beverages	application(s) -
relevant disease(s) neurological disorders; cardiovascular diseases	relevant disease(s) neurological disorders; cardiovascular diseases	relevant disease(s) -	relevant disease(s) -

一般描述

A useful tool for the synthesis of branched, side-chain modified, cyclic peptides and peptide tools for click chemistry. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols^[1] or phosphines^[2,3].

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references

^[1]M. Meldal, et al. (1997) Tetrahedron Lett., 38, 2531.
^[2] J. T. Lundquist & J. C. Pelletier (2001) Org. Lett.,3, 781.
^[3] N. Nepomniaschiy, et al. (2008) Org.Lett., 10, 5243.

分析说明

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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商品

Selecting Orthogonal Building Blocks

Novabiochem^® offers orthogonally protected amino acids for peptide synthesis, including cyclic and branched peptides.

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(2S,3S)-Fmoc-Abu(3-N3)-OH