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主要文件

8.52339

Sigma-Aldrich

Fmoc-Pen(Trt)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem®

别名:

Fmoc-Pen(Trt)-OH, Fmoc-α, α-dimethyl-Cys(Trt)-OH,Fmoc-S-trityl-L-penicillamine

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About This Item

经验公式(希尔记法):
C39H35NO4S
分子量:
613.76
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.22

产品名称

Fmoc-Pen(Trt)-OH, Novabiochem®

质量水平

产品线

Novabiochem®

方案

≥98% (TLC)
≥98.0% (HPLC)

表单

powder

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

thiol

储存温度

15-25°C

SMILES字符串

S(C([C@H](NC(=O)OCC4c5c(cccc5)c6c4cccc6)C(=O)O)(C)C)C(c3ccccc3)(c2ccccc2)c1ccccc1

InChI

1S/C39H35NO4S/c1-38(2,45-39(27-16-6-3-7-17-27,28-18-8-4-9-19-28)29-20-10-5-11-21-29)35(36(41)42)40-37(43)44-26-34-32-24-14-12-22-30(32)31-23-13-15-25-33(31)34/h3-25,34-35H,26H2,1-2H3,(H,40,43)(H,41,42)/t35-/m1/s1

InChI key

XSGMGAINOILNJR-PGUFJCEWSA-N

一般描述

Fmoc-Pen(Trt)-OH is the standard building block for the introduction of penicillamine amino-acid residues by Fmoc SPPS. The side-chain thiol protecting group (Trt) is removed during the standard TFA-mediated cleavage reaction.

Associated Protocols and Technical Articles:
Cleavage and Deprotection Protocols for Fmoc SPPS

应用

Fmoc-Pen(Trt)-OH has been recently used in the synthesis of disulfide surrogate peptides.

分析说明

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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