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Merck
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安全信息

8.52244

Sigma-Aldrich

Fmoc-D-Ser(PO(OBzl)OH)-OH

for peptide synthesis, Novabiochem®

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别名:
Fmoc-D-Ser(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-D-phosphoserine
经验公式(希尔记法):
C25H24NO8P
分子量:
497.43
UNSPSC代码:
12352209
NACRES:
NA.22

质量水平

产品线

Novabiochem®

形式

solid

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

Fmoc

储存温度

15-25°C

一般描述

Novabiochem®
An excellent building block for the preparation of D-phosphoserine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOP® and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Peptides containing Post-Translational Modifications

联系

Replaces: 04-13-1078

分析说明

Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +9.5 - +12.5 °
Purity (TLC(CMA1)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 %
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 2.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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实验方案

We provide an overview of our available reagents, together with recommendations and details of their use for synthesis of peptides containing post-translationally modified amino acids.

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