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Merck
CN
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文件

8.52216

Sigma-Aldrich

Fmoc-Dpr(Boc-Aoa)-OH

Novabiochem®

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别名:
Fmoc-Dpr(Boc-Aoa)-OH, N-α-Fmoc-N-β-(N-t.-Boc-amino-oxyacetyl)-L-diaminopropionic acid
经验公式(希尔记法):
C25H29N3O8
分子量:
499.51
UNSPSC代码:
12352209
NACRES:
NA.22

质量水平

产品线

Novabiochem®

检测方案

≥95.0% (acidimetric)
≥96.0% (HPLC)
≥98% (TLC)

形式

powder

反应适用性

reagent type: ligand

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

Boc
Fmoc

储存温度

2-30°C

InChI

1S/C25H29N3O8/c1-25(2,3)36-24(33)28-35-14-21(29)26-12-20(22(30)31)27-23(32)34-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,26,29)(H,27,32)(H,28,33)(H,30,31)/t20-/m0/s1

InChI key

KHRQNEDYPNTPKW-FQEVSTJZSA-N

一般描述

An excellent derivative for the chemoselective ligation of unprotected peptides in aqueous media [1] via oxime formation. This derivative introduces a hydroxylamine functionality which can couple with aldehyde groups present in another peptide unit.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

[1] F. Wahl & M. Mutter (1996) Tetrahedron Lett., 37, 6861.

联系

Replaces: 04-12-1185

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 96.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 2.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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