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主要文件

安全信息

8.52208

Sigma-Aldrich

Fmoc-3,4-dehydro-Pro-OH

Novabiochem®

别名:

Fmoc-3,4-dehydro-Pro-OH, N-α-Fmoc-3,4-dehydro-L-proline

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About This Item

经验公式(希尔记法):
C20H17NO4
分子量:
335.35
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.22

质量水平

产品线

Novabiochem®

方案

≥85.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

表单

powder

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

Fmoc

储存温度

15-25°C

SMILES字符串

N4([C@@H](C=CC4)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C20H17NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-10,17-18H,11-12H2,(H,22,23)/t18-/m0/s1

InChI key

OALUMAMYGOBVTF-SFHVURJKSA-N

一般描述

Standard building block for introduction of dehydroproline residues by Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

联系

Replaces: 04-12-1051

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 97.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 85.0 %
Water (K. F.): ≤ 5.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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