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Merck
CN

8.52039

Fmoc-Thi-OH

Novabiochem®

别名:

Fmoc-Thi-OH, N-α-Fmoc-β-thienyl-L-alanine

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关于此项目

经验公式(希尔记法):
C22H19NO4S
化学文摘社编号:
分子量:
393.46
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
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产品名称

Fmoc-Thi-OH, Novabiochem®

SMILES string

[s]1c(ccc1)C[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)[O-]

InChI

1S/C22H19NO4S/c24-21(25)20(12-14-6-5-11-28-14)23-22(26)27-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-11,19-20H,12-13H2,(H,23,26)(H,24,25)/p-1/t20-/m0/s1

InChI key

PXBMQFMUHRNKTG-FQEVSTJZSA-M

product line

Novabiochem®

assay

≥96.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

170-180 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

Quality Level

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(157B)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

General description

Standard building block for introduction of thienylalanine by Fmoc SPPS. Useful replacement for Phe.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Other Notes

Replaces: 04-12-1082

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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