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8.52003

Sigma-Aldrich

Fmoc-Ala-OH

Novabiochem®

别名:

Fmoc-Ala-OH, N-α-Fmoc-L-alanine monohydrate

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About This Item

经验公式（希尔记法）:
C18H17NO4
CAS号:
35661-39-3
分子量:
311.33
MDL编号:
MFCD00037139
UNSPSC代码:
12352209
EC索引号:
252-660-6
NACRES:
NA.22

质量水平

400

产品线

Novabiochem®

方案

≥93.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)

表单

powder

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

mp

140-150 °C

应用

peptide synthesis

官能团

Fmoc

储存温度

2-30°C

SMILES字符串

N(C(C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)

InChI key

QWXZOFZKSQXPDC-UHFFFAOYSA-N

相关类别

一般描述

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of alanine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

应用

  • Interface Passivation of Perovskite Solar Cells by Fmoc-Ala-OH Amino Acids: This study explores the effects of Fmoc-Ala-OH on perovskite solar cells, showing its potential to improve the efficiency and stability of these devices (Song et al., 2023).
  • Charge and Sequence Effects on the Self-Assembly and Subsequent Hydrogelation of Fmoc-depsipeptides: Discusses the role of Fmoc-Ala-OH in the self-assembly processes necessary for creating advanced materials, highlighting its utility in material science (Nguyen et al., 2014).
  • High-Quality Conjugated Polymers Achieving Ultra-Trace Detection of Cr2O72- in Agricultural Products: Illustrates the application of Fmoc-Ala-OH in the development of sensitive detection systems for environmental monitoring (Li et al., 2022).
  • A Liquid-Phase Continuous-Flow Peptide Synthesizer for Preparing C-terminal Free Peptides: Details how Fmoc-Ala-OH is used in innovative peptide synthesis technologies to streamline production processes in pharmaceutical applications (Otake et al., 2023).
  • Self-assembled Structures Formed by Fmoc Modified Aliphatic Amino Acids: Examines the use of Fmoc-Ala-OH in the formation of self-assembled structures, which are crucial for developing new materials with tailored properties (Gour et al., 2021).

联系

Replaces: 04-12-1006

分析说明

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Ala-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 93.0 %
Water (K. F.): ≤ 6.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Yun Song et al.
Cell reports, 30(8), 2699-2711 (2020-02-27)
The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the

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