产品名称
Bis-Boc-amino-oxyacetic acid, Novabiochem®
product line
Novabiochem®
assay
≥97% (TLC)
form
powder
reaction suitability
reagent type: ligand
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
Analysis Note
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 97 %
Water (K. F.): 3.0 - 8.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 97 %
Water (K. F.): 3.0 - 8.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
General description
This reagent can be used to introduce a hydroxylamine functionality to N-terminal or side-chain amino groups. Hydroxylamine-labeled peptides prepared in this manner can be ligated in aqueous solution at pH 3.5 to aldehyde-containing peptides via oxime formation. This bis-protected derivative eliminates oligomer formation which can occur with mono-protected hydroxylamine reagents as a result of double acylation. Coupling of this derivative should be done using an OSu ester.
Literature references
[1] J. C. Spetzler & T. Hoeg-Jensen (2001) J. Peptide Sci., 7, 537.
Literature references
[1] J. C. Spetzler & T. Hoeg-Jensen (2001) J. Peptide Sci., 7, 537.
Other Notes
Replaces: 01-63-0129
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
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