推荐产品
产品名称
DSC, N,N′-Disuccinimidyl carbonate Novabiochem®
质量水平
产品线
Novabiochem®
方案
≥99.0% (HPLC)
表单
powder
反应适用性
reaction type: Coupling Reactions
制造商/商品名称
Novabiochem®
mp
188-191 °C
应用
peptide synthesis
储存温度
2-8°C
SMILES字符串
N2(C(=O)CCC2=O)OC(=O)ON1C(=O)CCC1=O
InChI
1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2
InChI key
PFYXSUNOLOJMDX-UHFFFAOYSA-N
一般描述
A convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids [1,2,3,4].
Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents
Literature references
[1] H. Ogura, et al. (1979) Tetrahedron Lett., 20, 4745.
[2] H. Ogura, et al. (1981) Tetrahedron Lett., 22, 4817.
[3] K. Takeda, et al. (1982) Synth. Commun., 12, 213.
[4] K. Takeda, et al. (1983) TetrahedronLett., 24, 4569.
Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents
Literature references
[1] H. Ogura, et al. (1979) Tetrahedron Lett., 20, 4745.
[2] H. Ogura, et al. (1981) Tetrahedron Lett., 22, 4817.
[3] K. Takeda, et al. (1982) Synth. Commun., 12, 213.
[4] K. Takeda, et al. (1983) TetrahedronLett., 24, 4569.
应用
- Utilization in solid-phase peptide synthesis: Discusses the role of N,N′-disuccinimidyl carbonate in solid-phase peptide synthesis, providing insights into its effectiveness in enhancing coupling reactions (Meschaninova et al., 2019).
- Surface functionalization of polymeric materials: This article explores the application of N,N′-disuccinimidyl carbonate in the surface functionalization of polymers to improve their biocompatibility and interaction with biological molecules (Yakufu et al., 2020).
- Development of affinity chromatography technologies: Details the use of N,N′-disuccinimidyl carbonate in the development of novel affinity chromatography approaches for protein purification (Hinamoto et al., 2023).
- Enhancement of polymer properties: Investigates how N,N′-disuccinimidyl carbonate can be used to modify polymer surfaces to enhance their properties, such as increased hydrophilicity and reactivity (Swar et al., 2020).
联系
Replaces: 01-62-0006
分析说明
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 0.50 %
Identity (IR): passes test
Appearance of substance (visual): powder
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 0.50 %
Identity (IR): passes test
法律信息
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - STOT RE 2 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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