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Merck
CN
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文件

安全信息

8.43943

Sigma-Aldrich

Propanephosphonic acid anhydride

(50% solution in 2-Methyltetrahydrofuran) for synthesis T3P

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别名:
2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, Propylphosphonic anhydride, T3P
UNSPSC代码:
12352108
NACRES:
NA.22

质量水平

200

形式

liquid

bp

78-80 °C/1013 hPa (solvent)

转变温度

flash point -11 °C (solvent)

密度

1.039 g/cm3 at 20 °C

储存温度

2-8°C

应用


  • Study on the propylphosphonic anhydride (T3P) mediated Ugi-type three-component reaction. Efficient synthesis of an α-amino amide library: Explores the use of T3P in a three-component Ugi reaction, demonstrating its utility in synthesizing a diverse library of α-amino amides (Milen et al., 2017).

  • Cyclization of Linear Tetrapeptides Containing N‐Methylated Amino Acids by using 1‐Propanephosphonic Acid Anhydride: Reports the unexpected findings during the cyclization of linear tetrapeptides, where T3P played a crucial role in enhancing the reaction outcomes (Zhang et al., 2017).


分析说明

Assay (T3P) (NMR): ≥ 40.0 %
Pyropropanephosphonic acid (NMR): ≤ 10.0 %
Propanephosphonic acid (NMR): ≤ 0.50 %
2- Methyltetrahydrofurane (calculated): ≤ 50.0 %

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