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Merck
CN
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主要文件

8.40124

Sigma-Aldrich

Span® 85

for synthesis

别名:

Span® 85

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About This Item

经验公式（希尔记法）:
C60H108O8
CAS号:
26266-58-0
分子量:
957.49
MDL编号:
MFCD00133820
UNSPSC代码:
12352108
EC索引号:
247-569-3
NACRES:
NA.22

蒸汽压

<1.4 hPa ( 20 °C)

质量水平

200

表单

liquid

效能

39800 mg/kg LD50, oral (Rat)

运动粘度

120 cSt(40 °C)

转变温度

flash point 225 °C

溶解性

insoluble <0.001 g/L

密度

0.95 g/cm3 at 20 °C

储存温度

2-30°C

SMILES字符串

O1[C@@H]([C@H]([C@@H](C1)O)OC(=O)CCCCCCC\C=C/CCCCCCCC)C(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-/t54-,55?,59+,60-/m1/s1

InChI key

PRXRUNOAOLTIEF-XDTJCZEISA-N

应用


  • Macromolecular Stabilization: Span® 85 is used as a stabilizer for the preparation of PMMA colloidal particles in nonpolar media, proving effective in maintaining stability under various conditions, crucial for industrial applications in coatings and advanced materials manufacturing (Liu et al., 2022).

  • Enhanced Nanoemulsion Systems: It plays a critical role in the formation of aerosolized nanoemulsion systems encapsulating docetaxel and curcumin, utilized in cancer therapy to improve therapeutic outcomes through enhanced drug delivery mechanisms (Abdul Rahman et al., 2020).

  • Skin Protection Formulations: Span® 85 is integral in the formulation and clinical assessment of microemulsion-based hydrogels for UV protection, demonstrating its utility in skincare products by enhancing sun protection factor and skin compatibility (Ebrahimi et al., 2019).

  • Transdermal Drug Delivery: This surfactant is utilized in tailoring novel soft nano-vesicles, known as ′Flexosomes′, to enhance transdermal drug delivery, which is pivotal for non-invasive therapeutic applications and improving patient compliance (Mansour et al., 2019).

分析说明

羟值：55 - 75
皂化值：170 - 190
鉴别（IR）：符合检验
由于其特定的熔程，产物可以是固体、液体、固化熔体或过冷熔体。

法律信息

Span is a registered trademark of Croda International PLC

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

437.0 °F

闪点(°C)

225 °C

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