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Merck
CN

8.08259

2,2,2-Trifluoroethanol

for synthesis

别名:

2,2,2-Trifluoroethanol

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关于此项目

经验公式（希尔记法）:
C2H3F3O
化学文摘社编号:
75-89-8
分子量:
100.04
UNSPSC Code:
12352104
EC Index Number:
200-913-6
NACRES:
NA.22
MDL number:
MFCD00004672
Grade:
synthesis grade
Assay:
≥99% (GC)
Bp:
73.6 °C/1013 hPa
Vapor pressure:
70.9 hPa ( 20 °C)

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产品名称

2,2,2-Trifluoroethanol, for synthesis

SMILES string

FC(F)(F)CO

InChI

1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

InChI key

RHQDFWAXVIIEBN-UHFFFAOYSA-N

grade

synthesis grade

vapor pressure

70.9 hPa ( 20 °C)

assay

≥99% (GC)

form

liquid

potency

240 mg/kg LD50, oral (Rat)
1680 mg/kg LD50, skin (Rat)

expl. lim.

8.4-28.8 % (v/v)

dilution

(for synthesis)

pH

7

bp

73.6 °C/1013 hPa

mp

-43.5 °C

transition temp

flash point 30 °C

density

1.38 g/cm3 at 25 °C

storage temp.

2-30°C

Quality Level

200

Application

2,2,2-Trifluoroethanol is used as a solvent:
  • In the preparation of nylon/Ag composite nanofibers by electrospinning method.
  • To study the combination of two polymers PANI (polyaniline) and PHB (polyhydroxy-butyrate).

Features and Benefits

2,2,2-Trifluoroethanol is more acidic than ethanol due to the presence of electronegative trifluoromethyl group.

General description

2,2,2-Trifluoroethanol (TFE) is a fluorinated compound used as a solvent in organic synthesis. Peptides and proteins are experimentally studied using TEE as a cosolvent. In TFE, hydrogen peroxide is effective for oxidizing sulfur compounds.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation

target_organs

Blood

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

86.0 °F - closed cup

flash_point_c

30 °C - closed cup

法规信息

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实验方案

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Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.

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A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

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