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安全信息

8.08259

Sigma-Aldrich

2,2,2-Trifluoroethanol

for synthesis

别名:

2,2,2-Trifluoroethanol

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About This Item

经验公式(希尔记法):
C2H3F3O
CAS号:
分子量:
100.04
MDL编号:
UNSPSC代码:
12352104
EC索引号:
200-913-6
NACRES:
NA.22

蒸汽压

70.9 hPa ( 20 °C)

质量水平

检测方案

≥99% (GC)

形式

liquid

效能

240 mg/kg LD50, oral (Rat)
1680 mg/kg LD50, skin (Rat)

expl. lim.

8.4-28.8 % (v/v)

pH值(酸碱度)

7

bp

73.6 °C/1013 hPa

mp

-43.5 °C

转变温度

flash point 30 °C

密度

1.38 g/cm3 at 25 °C

储存温度

2-30°C

InChI

1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

InChI key

RHQDFWAXVIIEBN-UHFFFAOYSA-N

一般描述

2,2,2-Trifluoroethanol (TFE) is a fluorinated compound used as a solvent in organic synthesis. Peptides and proteins are experimentally studied using TEE as a cosolvent. In TFE, hydrogen peroxide is effective for oxidizing sulfur compounds.

应用

2,2,2-Trifluoroethanol is used as a solvent:
  • In the preparation of nylon/Ag composite nanofibers by electrospinning method.
  • To study the combination of two polymers PANI (polyaniline) and PHB (polyhydroxy-butyrate).

特点和优势

2,2,2-Trifluoroethanol is more acidic than ethanol due to the presence of electronegative trifluoromethyl group.

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation

靶器官

Blood

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

86.0 °F - closed cup

闪点(°C)

30 °C - closed cup

法规信息

危险化学品

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实验方案

Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.

A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

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