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Merck
CN
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文件

安全信息

8.01636

Sigma-Aldrich

溴乙酸乙酯

for synthesis

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别名:
溴乙酸乙酯
经验公式(希尔记法):
C4H7BrO2
CAS号:
分子量:
167.00
MDL编号:
UNSPSC代码:
12352108
EC索引号:
203-290-9
NACRES:
NA.22

蒸汽压

4.5 hPa ( 20 °C)

质量水平

检测方案

≥98.0% (GC)

形式

liquid

bp

158-161 °C/1013 hPa

mp

-38 °C

转变温度

flash point 50 °C

密度

1.50 g/cm3 at 20 °C

储存温度

2-30°C

InChI

1S/C4H7BrO2/c1-2-7-4(6)3-5/h2-3H2,1H3

InChI key

PQJJJMRNHATNKG-UHFFFAOYSA-N

应用

  • Synthesis and anticancer potential of thiazolidinone and thiadiazole derivatives: Ethyl bromoacetate was utilized in the synthesis of new thiazolidinone and thiadiazole derivatives, which were subsequently evaluated for their anticancer properties through molecular docking studies. This application highlights its role in the development of potential anticancer agents (Saeed et al., 2024).
  • Development of pyrazolopyranopyrimidine derivatives: Research on the synthesis of novel pyrazolopyranopyrimidine derivatives involved ethyl bromoacetate, focusing on their structural and dynamic properties using crystallography, DFT calculations, and molecular dynamics simulations, contributing to the field of medicinal chemistry (Ait Elmachkouri et al., 2023).
  • Eco-friendly insecticidal derivatives for olive pest control: Ethyl bromoacetate was employed in the design and synthesis of pyridine and thiazole derivatives aimed at providing eco-friendly insecticidal solutions for controlling olive pests, demonstrating its utility in agricultural chemistry (Elkanzi et al., 2023).
  • DNA-compatible synthesis of thiazolidione derivatives: A study used ethyl bromoacetate in a DNA-compatible three-component annulation and Knoevenagel condensation process to synthesize thiazolidione derivatives, showcasing its versatility in complex organic syntheses (Wang et al., 2023).
  • Accidental discovery of macrocycles: Ethyl bromoacetate played a role in the serendipitous discovery of new macrocycles containing amide, amino, and carbamate groups during a residue separation process, illustrating its potential in unexpected synthetic outcomes (Horita et al., 2023).

分析说明

含量测定(GC,面积%): ≥ 98.0 %(a/a)
密度(d 20 °C/ 4 °C):1.500 - 1.510
鉴别(IR):符合检验

象形图

FlameSkull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Flam. Liq. 3

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

116.6 °F - closed cup

闪点(°C)

47 °C - closed cup

法规信息

危险化学品

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