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Merck
CN
所有图片(1)

文件

8.01336

Sigma-Aldrich

Pivalic acid

for synthesis

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别名:
Pivalic acid, Neopentanoic acid, 2,2-Dimethylpropionic acid, Trimethylacetic acid
线性分子式:
(CH3)3CCOOH
CAS号:
分子量:
102.13
MDL编号:
UNSPSC代码:
12352106
EC索引号:
200-922-5
NACRES:
NA.22

蒸汽压

0.85 hPa ( 20 °C)

质量水平

形式

crystals

效能

900 mg/kg LD50, oral (Rat)
1900 mg/kg LD50, skin (Rat)

expl. lim.

1.6 % (v/v)

mp

32-35 °C

转变温度

flash point 64 °C

溶解性

25 g/L

密度

0.91 g/cm3 at 20 °C

储存温度

2-30°C

InChI

1S/C5H10O2/c1-5(2,3)4(6)7/h1-3H3,(H,6,7)

InChI key

IUGYQRQAERSCNH-UHFFFAOYSA-N

相关类别

应用


  • Regiodivergent synthesis involving pivalic acid: A ligand-controlled regiodivergent C-H alkenylation process using pivalic acid, advancing the synthesis of complex indazoles and potentially impacting pharmaceutical compound development (Kim et al., 2017).

  • Pivalic acid in radiochemical syntheses: The study utilized pivalic acid derivatives for the synthesis of novel radioiodinated pharmaceuticals for hypoxia imaging, highlighting its utility in diagnostic and therapeutic applications in the medical field (Elsaidi et al., 2019).

  • Capillary electrophoretic applications of pivalic acid: Research explored new methods of cationic electrophoretic focusing using pivalic acid for high-sensitivity analysis of water contaminants, providing insights into environmental monitoring techniques (Malá and Gebauer, 2022).

  • Cyclative coupling using pivalic acid: Zhuang et al. described a novel cyclative C-H/C-H coupling technique facilitated by pivalic acid, which rapidly constructs complex molecular frameworks like tetralin and chromane, useful in drug discovery and development (Zhuang et al., 2021).

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

147.2 °F - closed cup

闪点(°C)

64 °C - closed cup


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