676493
VEGF Inhibitor, Flt2₋11
The VEGF Inhibitor, Flt2-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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所有图片(1)
别名:
VEGF Inhibitor, Flt2₋11, NITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I
经验公式（希尔记法）:
C61H104N14O15
分子量:
1273.56
UNSPSC代码:
12352200
NACRES:
NA.77
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质量水平
检测方案
≥95% (HPLC)
形式
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white
溶解性
acetonitrile: 20%
DMSO: 5 mg/mL
运输
ambient
储存温度
2-8°C
一般描述
An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is reported to inhibit angiogenesis in chick chorioallantoic membrane and VEGF-induced vascular permeability. Does not bind to vascular endothelial growth factor (VEGF) nor inhibit its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.
An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is shown to inhibit angiogenesis in chick chorioallantoic membrane and inhibits VEGF-induced vascular permeability. Neither binds to vascular endothelial growth factor (VEGF) nor inhibits its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.
生化/生理作用
Cell permeable: no
Primary Target
VEGF
VEGF
Product does not compete with ATP.
Reversible: no
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
序列
H-Asn-Ile-Thr-Val-Thr-Leu-Lys-Lys-Phe-Pro-Leu-OH
其他说明
Tan, D.C., et al. 2001. FEBS Lett.494, 150.
法律信息
Sold under license of U.S. Patent 6,200,954.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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