推荐产品
方案
>98% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
DMSO: 100 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC50 of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Kartner, N., et al. 2010. J. Biol. Chem.285, 37476.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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