655207
吐温80(TWEEN® 80)
protein grade detergent, 10% solution, sterile-filtered, for immunoprecipitation and for the solubilization of membrane-bound proteins
别名:
POE (20)山梨糖醇酐单油酸酯, 聚乙二醇山梨醇酐单油酸酯, 聚山梨酯 80, 聚氧乙烯山梨糖醇酐单油酸酯
产品名称
吐温80(TWEEN® 80), protein grade detergent, 10% solution, sterile-filtered, for immunoprecipitation and for the solubilization of membrane-bound proteins
InChI
1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
SMILES string
CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
InChI key
RGPBUVUVZKQNHD-MDZDMXLPSA-N
description
Merck USA index - 14, 7582
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
aggregation number
58
impurities
≤200 μM Aldehyde
≤200 μM peroxide
color
clear colorless
CMC
12 μM (HLB number 15)
density
1.07 g/cm3 at 25 °C
shipped in
ambient
storage temp.
2-8°C
Quality Level
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Application
- Performance of β-carotene-loaded nanostructured lipid carriers under dynamic in vitro digestion system: Influence of the emulsifier type.: This paper discusses the performance of β-carotene-loaded nanostructured lipid carriers, where TWEEN 80 is utilized as an emulsifier. The study highlights its impact on the stability and bioaccessibility of β-carotene during digestion, offering valuable insights for food science and nutraceuticals applications (Lüdtke FL et al., 2024).
- Fabrication and characterization of transdermal delivery of ribociclib nanoemulgel in breast cancer treatment.: This study explores the use of TWEEN 80 in developing a transdermal nanoemulgel for the delivery of ribociclib, enhancing its therapeutic efficacy against breast cancer. The work focuses on innovative drug delivery systems that improve patient compliance and drug stability (Makeen HA et al., 2024).
- A novel antifungal nanoemulsion based on reuterin-assisted synergistic essential oils: Preparation and in vitro/in vivo characterization.: Here, TWEEN 80 is used to create a potent antifungal nanoemulsion, incorporating reuterin and essential oils. The study emphasizes the potential of nanoemulsions to significantly enhance the antifungal activity of natural compounds, promising applications in food preservation and safety (Nikkhah M et al., 2024).
- Development and characterization of edible and active coating based on xanthan gum nanoemulsion incorporating betel leaf extract for fresh produce preservation.: This investigation uses TWEEN 80 in a xanthan gum-based nanoemulsion, integrating betel leaf extract for the preservation of fresh produce. It highlights the role of such nanoemulsions in extending the shelf life of perishable foods, with significant implications for the food industry (Aayush K et al., 2024).
Disclaimer
Toxicity: Standard Handling (A)
General description
Conductivity:≤50 µmhos.
Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins (aggregation number: 58; conductivity: <50 µmhos; CMC: 12 µM; HLB number: 15). Supplied as a 10% (W/W) solution of PROTEIN GRADE TWEEN 80 detergent.
Packaging
Packaged under inert gas
Physical form
Supplied as a 10% (W/W) aqueous solution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
PROTEIN GRADE is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
>235.4 °F - closed cup
flash_point_c
> 113 °C - closed cup
Cristina Cigana et al.
Antimicrobial agents and chemotherapy, 60(8), 4991-5000 (2016-06-15)
The clinical development of antibiotics with a new mode of action combined with efficient pulmonary drug delivery is a priority against untreatable Pseudomonas aeruginosa lung infections. POL7001 is a macrocycle antibiotic belonging to the novel class of protein epitope mimetic
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