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一般描述
Diethylamine (DEA) is commonly used as an eluent additive in various chromatographic techniques, including reversed-phase high-performance liquid chromatography (HPLC), high pH reversed-phase preparative chromatography, and hydrophilic liquid chromatography (HILIC). It plays a crucial role in system efficiency and enhancing peak shape when used in column chromatography.
应用
Diethylamine can be used as a mobile phase modifierin the HILIC method for the simultaneous determination of paracetamol andmethionine in a soft capsule formulation.
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3
靶器官
Respiratory system
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
-14.8 °F - closed cup
闪点(°C)
-26 °C - closed cup
法规信息
新产品
A new analytical methodology for a fast evaluation of semi-volatile polycyclic aromatic hydrocarbons in the vapor phase downstream of a diesel engine particulate filter
Journal of Chromatography A, 1218(7), 981-989 (2011)
RP-HPLC ANALYSIS OF ACIDIC AND BASIC DRUGS IN SYSTEMS WITH DIETHYLAMINE AS ELUENTS ADDITIVE.
Petruczynik A, et al.
Acta Poloniae Pharmaceutica, 73(6), 1475-1485 (2016)
Separation of nadolol racemates by high pH reversed-phase preparative chromatography
Arafah RS, et al.
Separation and Purification Technology, 233, 116018-116018 (2020)
Peak shape enhancement using diethylamine in hydrophilic liquid interaction chromatography: Application in simultaneous determination of methionine and paracetamol
BinhVN, et al.
Journal of Pharmaceutical and Biomedical Analysis, 203, 114214-114214 (2021)
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