推荐产品
质量水平
方案
≥98% (TLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white
溶解性
ethanol: 5 mg/mL
methanol: 5 mg/mL
运输
ambient
储存温度
2-8°C
SMILES字符串
[S](=O)(=O)(N[C@@H](Cc2ccccc2)C(=O)CCl)c1ccc(cc1)C
InChI
1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1
InChI key
MQUQNUAYKLCRME-INIZCTEOSA-N
一般描述
Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharide (EC50 = 20 µM). Suggested working concentration is 10-100 µM.
This product has been discontinued.
Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides (EC50 = 20 M).
Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides (EC50 = 20 M).
生化/生理作用
Cell permeable: no
EC50 = 20 µM in blocking the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides.
Primary Target
chymotrypsin activity in preparations
chymotrypsin activity in preparations
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Irritant (B)
重悬
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
其他说明
Fearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun.215, 721.
Weaver, V.M., et al. 1993. Biochem. Cell Biol.71, 488.
Murakami, T., et al. 1991. Biochim. Biophys. Acta1079, 279.
Nierodzik, M.L., et al. 1991. J. Clin. Invest.87, 229.
Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.
Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun.215, 721.
Weaver, V.M., et al. 1993. Biochem. Cell Biol.71, 488.
Murakami, T., et al. 1991. Biochim. Biophys. Acta1079, 279.
Nierodzik, M.L., et al. 1991. J. Clin. Invest.87, 229.
Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门