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质量水平
检测方案
≥90% (SDS-PAGE)
形式
liquid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
运输
wet ice
储存温度
−70°C
一般描述
Native TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
Native TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
生化/生理作用
Cell permeable: no
Primary Target
MMP-1
MMP-1
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
外形
In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, pH 7.0.
制备说明
Prepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
其他说明
Greene, J., et al. 1996. J. Biol. Chem. 271, 30375.
Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
法律信息
Brij is a registered trademark of Croda International PLC
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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