质量水平
检测方案
≥95% (HPLC)
形式
liquid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
储存温度
−70°C
一般描述
Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20 µM in the presence of 1 mM ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC50 = 10-20 µM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.
包装
Packaged under inert gas
警告
Toxicity: Irritant (B)
外形
A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 572630) in DMSO.
重悬
Following initial thaw, aliquot and freeze (-70°C).
其他说明
Mohammadi, M., et al. 1997. Science 276, 955.
法律信息
Not available for sale in the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
闪点(°F)
188.6 °F
闪点(°C)
87 °C
Lydvina Meister et al.
Development (Cambridge, England), 149(10) (2022-05-17)
The fibroblast growth factor (FGF) signalling pathway plays various roles during vertebrate embryogenesis, from mesoderm formation to brain patterning. This diversity of functions relies on the fact that vertebrates possess the largest FGF gene complement among metazoans. In the cephalochordate
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门