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Merck
CN
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主要文件

567703

Sigma-Aldrich

Spermine NONOate

Complex of nitric oxide (NO) with spermine.

别名:

Spermine NONOate, N-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22

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About This Item

经验公式(希尔记法):
C10H26N6O2
分子量:
262.35
MDL编号:
UNSPSC代码:
12352200

质量水平

方案

≥98% (UV)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white

溶解性

0.1 M NaOH: soluble
water: soluble

运输

ambient

储存温度

−20°C

InChI

1S/C10H26N6O2/c11-5-3-8-13-7-1-2-9-15(10-4-6-12)16(18)14-17/h13,18H,1-12H2/p+3

InChI key

QPIOUFBAROSIAN-UHFFFAOYSA-Q

一般描述

Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½) of NO release = 230 min (PBS, pH 7.4, 22°C).
Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½)in PBS, pH 7.4 is 230 minutes at 22°C. Relatively stable in alkaline solution (≥pH 10.0).

生化/生理作用

Cell permeable: no
Primary Target
Convenient reagent for preparing aqueous solutions of NO
Product does not compete with ATP.
Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

其他说明

Ramamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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