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Merck
CN
所有图片(1)

主要文件

567540

Sigma-Aldrich

原钒酸钠

A broad spectrum potent inhibitor of protein tyrosine phosphatases.

别名:

原钒酸钠, PTP抑制剂X

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选择尺寸

1 L
CN¥1,177.27

CN¥1,177.27


预计发货时间October 20, 2025详情



选择尺寸

变更视图
1 L
CN¥1,177.27

About This Item

经验公式(希尔记法):
Na3O4V
CAS号:
分子量:
183.91
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.77

CN¥1,177.27


预计发货时间October 20, 2025详情


质量水平

描述

RTECS - YW1120000

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white to off-white

溶解性

water: 10 mg/mL

运输

ambient

储存温度

10-30°C

SMILES字符串

[V](=O)([O-])([O-])[O-].[Na+].[Na+].[Na+]

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此商品
A003MP9155L9037
technique(s)

cell attachment: suitable, cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

concentration

0.01 % (w/v), 0.1 mg/mL

concentration

-

concentration

-

concentration

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

300

mol wt

Mw 84000 Da

mol wt

-

mol wt

30,000-70,000

mol wt

-

form

liquid

form

liquid

form

lyophilized powder

form

crystalline powder

一般描述

一种广谱有效的蛋白质酪氨酸磷酸酶抑制剂。也可抑制Na+、K+ATP酶、酸性和碱性磷酸酶、磷酸果糖激酶和腺苷酸激酶。最近研究表明,在微摩尔范围内,可抑制鼠伤寒沙门氏菌麦芽糖(MalFGK2)重组结合蛋白依赖性ATP结合盒(ABC)转运体的ATP酶活性。可通过过氧化氢转化为过钒酸盐。

生化/生理作用

主要靶标
Na+、K+-ATP酶、酸性和碱性磷酸酶、磷酸果糖激酶和腺苷酸激酶
产物不与ATP竞争。
可逆:否
细胞可渗透性:否

警告

毒性:有害(C)

重悬

复溶后,等分并冷冻保存(-20°C)。贮备溶液在-20°C下可稳定保存至多3个月。

其他说明

Huyer, G., et al. 1997.J. Biol. Chem. 272, 843.
Hunke, S., et al. 1995.Biochem.Biophys.Res. Commun.216, 589.
Levchuck, S.G., et al. 1994.Pediatric Res.37, 382A.
Fohr, K.J., et al. 1989.Biochem.J.262, 83.
Swarup, G., et al. 1982.Biochem.Biophys.Res. Commun.107, 1104.
Seargeant, L.E. and Stinson, R.A.1979.Biochem.J.181, 247.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    商品

    Protein tyrosine phosphatases' catalytic mechanism involves transient phosphorylation.

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