推荐产品
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white to off-white
溶解性
water: 10 mg/mL
运输
ambient
储存温度
10-30°C
SMILES字符串
[V](=O)([O-])([O-])[O-].[Na+].[Na+].[Na+]
InChI
1S/3Na.4O.V/q3*+1;;3*-1;
InChI key
IHIXIJGXTJIKRB-UHFFFAOYSA-N
一般描述
一种广谱有效的蛋白质酪氨酸磷酸酶抑制剂。也可抑制Na+、K+-ATP酶、酸性和碱性磷酸酶、磷酸果糖激酶和腺苷酸激酶。在微摩尔范围内，还抑制鼠伤寒沙门氏菌麦芽糖（MalFGK2）重组结合蛋白依赖性ATP结合盒（ABC）转运体的ATP酶活性。可通过过氧化氢转化为过钒酸盐。
一种广谱有效的蛋白质酪氨酸磷酸酶抑制剂。也可抑制Na+、K+ATP酶、酸性和碱性磷酸酶、磷酸果糖激酶和腺苷酸激酶。最近研究表明，在微摩尔范围内，可抑制鼠伤寒沙门氏菌麦芽糖（MalFGK2）重组结合蛋白依赖性ATP结合盒（ABC）转运体的ATP酶活性。可通过过氧化氢转化为过钒酸盐。
生化/生理作用
主要靶标
Na+、K+-ATP酶、酸性和碱性磷酸酶、磷酸果糖激酶和腺苷酸激酶
Na+、K+-ATP酶、酸性和碱性磷酸酶、磷酸果糖激酶和腺苷酸激酶
产物不与ATP竞争。
可逆：否
细胞可渗透性：否
警告
毒性：有害（C）
重悬
复溶后，等分并冷冻保存（-20°C）。贮备溶液在-20°C下可稳定保存至多3个月。
其他说明
Huyer, G., et al. 1997.J. Biol. Chem. 272, 843.
Hunke, S., et al. 1995.Biochem.Biophys.Res. Commun.216, 589.
Levchuck, S.G., et al. 1994.Pediatric Res.37, 382A.
Fohr, K.J., et al. 1989.Biochem.J.262, 83.
Swarup, G., et al. 1982.Biochem.Biophys.Res. Commun.107, 1104.
Seargeant, L.E. and Stinson, R.A.1979.Biochem.J.181, 247.
Hunke, S., et al. 1995.Biochem.Biophys.Res. Commun.216, 589.
Levchuck, S.G., et al. 1994.Pediatric Res.37, 382A.
Fohr, K.J., et al. 1989.Biochem.J.262, 83.
Swarup, G., et al. 1982.Biochem.Biophys.Res. Commun.107, 1104.
Seargeant, L.E. and Stinson, R.A.1979.Biochem.J.181, 247.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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