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Merck
CN
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文件

565191

Sigma-Aldrich

Anti-Serum Amyloid P Component Rabbit pAb

liquid, Calbiochem®

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别名:
Anti-SAP
UNSPSC代码:
12352203
NACRES:
NA.43

生物来源

rabbit

抗体形式

serum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

liquid

包含

≤0.1% sodium azide as preservative

种属反应性

human

请勿与下列物质发生反应

mouse

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
avoid repeated freeze/thaw cycles

同位素/亚型

IgG

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

一般描述

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes serum amyloid P component.
Recognizes serum amyloid P component.
  • Antibody Target Gene Symbol: APCS
  • Target Synonym: MGC88159, PTX2, SAP, Serum amyloid p-component
  • Entrez Gene Name: amyloid P component, serum
  • Hu Entrez ID: 325
  • Mu Entrez ID: 20219
  • Rat Entrez ID: 29339
    • This Anti-Serum Amyloid P Component Rabbit pAb is validated for use in ELISA, Immunoelectrophoresis, IF, IHC, Ouchterlony, Radial Immunodiffusion for the detection of Serum Amyloid P Component.

    免疫原

    Human
    purified human SAP component

    应用

    ELISA (see comments)

    Immunoelectrophoresis (see comments)

    Immunofluorescence (1:20-1:50)

    Immunohistochemistry (1:200)

    Ouchterlony (see comments)

    Radial Immunodiffusion (see comments)

    警告

    Toxicity: Standard Handling (A)

    外形

    Undiluted serum.

    重悬

    Following initial thaw, aliquot and freeze (-20°C).

    其他说明

    Monospecific for serum amyloid P as determined by ouchterlony and immunoelectrophoresis. Immunofluorescence and immunoperoxidase staining of human tissues specifically identifies only those structures known to contain SAP. This antibody has also been reported to work for ELISA and radial immunodiffusion. Variables associated with assay conditions will dictate the optimal working dilution.
    Serban, D., and Rordorf-Adam, C. 1986. J. Immunol. Methods90, 159.
    Pepys, M.B., et al. 1979. Nature278, 259.

    法律信息

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    WGK

    WGK 1

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    Andrea Doni et al.
    Nature communications, 12(1), 3739-3739 (2021-06-20)
    Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component of the humoral arm of innate immunity involved in resistance to bacterial infection and regulation of tissue remodeling. Here we investigate the role of SAP
    Katrine Pilely et al.
    Frontiers in immunology, 8, 1040-1040 (2017-09-14)
    Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component

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