推荐产品
方案
≥97% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
颜色
white to off-white
溶解性
water: 50 mg/mL
运输
ambient
储存温度
2-8°C
一般描述
一种显示抗肿瘤特性的氟喹诺酮类抗菌化合物。显示与miRNA生物合成蛋白TAR RNA结合蛋白质2（TRBP；Kd = 12.56 µM）结合，增强RNAi并刺激miRNA表达。在一组12个癌细胞（HCT-116细胞中EC50为124 µM）中特异性诱导细胞周期阻滞和凋亡，并在异种移植小鼠模型（10 mg/kg，i.p.）中抑制肿瘤生长。
包装
用惰性气体包装
警告
毒性：标准处理（A）
重悬
复溶后，等分并冷冻保存（-20°C）。贮备溶液在-20°C下可稳定保存至多1年。
其他说明
Melo, S., et al. 2011.Proc.Natl.Acad.Sci. USA108, 4394.
Zhang, Q., et al. 2008.Cell Res.18, 1077.
Shan, G., et al. 2008.Nat. Biotechnol.26, 933.
Zhang, Q., et al. 2008.Cell Res.18, 1077.
Shan, G., et al. 2008.Nat. Biotechnol.26, 933.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Francesco Greco et al.
Non-coding RNA, 9(3) (2023-06-27)
Virus-encoded microRNAs were first reported in the Epstein-Barr virus in 2004. Subsequently, a few hundred viral miRNAs have been identified, mainly in DNA viruses belonging to the herpesviridae family. To date, only 30 viral miRNAs encoded by RNA viruses are
Bidur Paudel et al.
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Alzheimer's disease (AD) is characterized by progressive neurodegeneration, but the specific events that cause cell death remain poorly understood. Death Induced by Survival gene Elimination (DISE) is a cell death mechanism mediated by short (s) RNAs acting through the RNA-induced
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