552233
利多卡因 N-乙基溴
≥99% (HPLC), lyophilized solid, voltage-sensitive Na+ conductance blocker, Calbiochem®
别名:
利多卡因 N-乙基溴
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关于此项目
经验公式（希尔记法）:
C16H27BrN2O
化学文摘社编号:
分子量:
343.30
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
利多卡因 N-乙基溴, A quaternary lidocaine derivative, permanently charged, and lipophobic.
SMILES string
[N+](CC)(CC)(CC)CC(=O)Nc1c(cccc1C)C
InChI
1S/C16H26N2O/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5/h9-11H,6-8,12H2,1-5H3/p+1
InChI key
PYEBKOFMWAMBFV-UHFFFAOYSA-O
assay
≥99%
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
solubility
water: 3 mg/mL
shipped in
ambient
storage temp.
10-30°C
Quality Level
相关类别
Biochem/physiol Actions
产物不与ATP竞争。
可逆：否
在神经生理学测试中具有完全的活性
细胞渗透性：否
首要靶标
电压敏感性Na+电导的一种强大阻断剂
电压敏感性Na+电导的一种强大阻断剂
Disclaimer
毒性：刺激性（B）
General description
一种季铵盐利多卡因衍生物，带永久电荷且疏脂。在胞内使用时是电压敏感性Na+电导的一种强大阻断剂。抑制从细胞膜内部产生Na+依赖性尖峰，而不会影响Ca2+电流或谷氨酸激活的电流。
Other Notes
Mooney, R. 1992.J. Neurosci.12, 2464.
Regehr, W.G. and Tank, D.W.1992.J. Neurosci.12, 4202.
Regehr, W.G. and Tank, D.W.1992.J. Neurosci.12, 4202.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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