product name
利多卡因 N-乙基溴, A quaternary lidocaine derivative, permanently charged, and lipophobic.
质量水平
检测方案
≥99%
形式
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
溶解性
water: 3 mg/mL
运输
ambient
储存温度
10-30°C
InChI
1S/C16H26N2O/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5/h9-11H,6-8,12H2,1-5H3/p+1
InChI key
PYEBKOFMWAMBFV-UHFFFAOYSA-O
一般描述
一种季铵盐利多卡因衍生物，带永久电荷且疏脂。在胞内使用时是电压敏感性Na+电导的一种强大阻断剂。抑制从细胞膜内部产生Na+依赖性尖峰，而不会影响Ca2+电流或谷氨酸激活的电流。
生化/生理作用
产物不与ATP竞争。
可逆：否
在神经生理学测试中具有完全的活性
细胞渗透性：否
首要靶标
电压敏感性Na+电导的一种强大阻断剂
电压敏感性Na+电导的一种强大阻断剂
警告
毒性：刺激性（B）
其他说明
Mooney, R. 1992.J. Neurosci.12, 2464.
Regehr, W.G. and Tank, D.W.1992.J. Neurosci.12, 4202.
Regehr, W.G. and Tank, D.W.1992.J. Neurosci.12, 4202.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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