Protein C, Human Plasma

Native protein C from human plasma. Sold as a zymogen. Markedly prolongs kaolin-cephalin clotting time of normal plasma. Activated by α-thrombin to serine protease-activated protein C. In its active form, it is a potent anticoagulant that acts through selective inactivation of Factors Va and VIIIa.

Toxicity: Standard Handling (A)

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM benzamidine, pH 7.4.

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Following initial thaw, aliquot and freeze (-70°C).

Esmon, N.L., et al. 1999. Haematologica 84, 363.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.