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质量水平
方案
≥99% (TLC)
表单
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white
溶解性
aqueous buffer: 10 mg/mL
water: soluble
运输
ambient
储存温度
−20°C
SMILES字符串
[Na].[P](=O)(OC[C@H]3O[C@H]([C@@H]([C@@H]3O)O)[n]4c5ncnc(c5nc4)O)(O)O.[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)N2C=CC(=NC2=O)N)(O)O
InChI
1S/C10H13N4O8P.C9H14N3O8P.Na/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);/t
InChI key
GETQKWBYQAUFQM-VRQAYDGLSA-N
一般描述
减色性：≥在248 nm处40% 。
已知可诱导干扰素产生。
应用
- Penaeus monodon Interferon Regulatory Factor (PmIRF) Activates IFNs and Antimicrobial Peptide Expression via a STING-Dependent DNA Sensing Pathway.: This study explores the role of PmIRF in shrimp immune responses, specifically how it activates interferons and antimicrobial peptides through the STING-dependent DNA sensing pathway, enhancing antiviral defenses. (Soponpong et al., 2021).
- Identification, expression profiling of a grass carp TLR8 and its inhibition leading to the resistance to reovirus in CIK cells.: This article focuses on the TLR8 receptor in grass carp, its expression profiles, and how its inhibition confers resistance to reovirus in fish cell lines, providing insights into antiviral immunity in aquatic species. (Chen et al., 2013).
- Identification and expression profiles of ADAR1 gene, responsible for RNA editing, in responses to dsRNA and GCRV challenge in grass carp (Ctenopharyngodon idella).: The study examines the ADAR1 gene involved in RNA editing in grass carp, highlighting its response to double-stranded RNA and grass carp reovirus, shedding light on fish immune mechanisms. (Yang et al., 2012).
- Immune activation and target organ damage are consequences of hydrodynamic treatment but not delivery of naked siRNAs in mice.: This research differentiates the effects of hydrodynamic treatment and naked siRNA delivery in mice, showing that immune activation and organ damage are associated with the treatment method rather than the siRNAs themselves. (Rácz et al., 2011).
警告
毒性：标准处理（A）
重悬
复溶后，等分并冷冻保存（-20°C）。贮备液在-20°C下可稳定保存至多6个月。
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Xiang Chen et al.
Cellular & molecular immunology, 17(1), 76-84 (2018-10-03)
Epigenetic modification, including histone modification, precisely controls target gene expression. The posttranscriptional regulation of the innate signaling-triggered production of inflammatory cytokines and type I interferons has been fully elucidated, whereas the roles of histone modification alteration and epigenetic modifiers in
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