推荐产品
质量水平
方案
≥98% (TLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
water: 30 mg/mL
运输
ambient
储存温度
2-8°C
SMILES字符串
[nH]1c2c(c(c1)C[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cccc2
InChI
1S/C16H19N3O5/c17-11(7-9-8-18-12-4-2-1-3-10(9)12)15(22)19-13(16(23)24)5-6-14(20)21/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24)/t11-,13-/m0/s1
InChI key
PWIQCLSQVQBOQV-AAEUAGOBSA-N
一般描述
A cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD = ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
A cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
生化/生理作用
Cell permeable: yes
Primary Target
PPARγ
PPARγ
Product does not compete with ATP.
Reversible: yes
kd = ~ 8 µM as PPARγ antagonist
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
制备说明
Addition of a small amount of acid or base may be required for complete solubilization.
重悬
Following reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
其他说明
Ye, F., et al. 2006. Chembiochem7, 74.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门