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Merck
CN
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文件

516090-M

Millipore

Penciclovir

A carba analog of Ganciclovir. Active against several herpes viruses. Induces apoptosis effectively without exerting much genotoxicity.

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别名:
Penciclovir, 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one
经验公式（希尔记法）:
C10H15N5O3
CAS号:
39809-25-1
分子量:
253.26
MDL编号:
MFCD15142866
UNSPSC代码:
12352200

质量水平

100

检测方案

≥98% (HPLC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white

溶解性

water: 1 mg/mL
aqueous buffer, pH 2.0: 10 mg/mL

储存温度

−20°C

InChI

1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)

InChI key

JNTOCHDNEULJHD-UHFFFAOYSA-N

一般描述

A carba analog of Ganciclovir (Cat. No. 345700). Active against several herpes viruses (IC50 = 37.9 µM for HHV-6A and 77.8 µM for HHV-6B). Induces apoptosis effectively without exerting much genotoxicity.
A synthetic acyclic guanine derivative and a carba analog of Ganciclovir (Cat. No. 345700) that is active against several herpes viruses (IC50 = 37.9 µM for HHV-6A and 77.8 µM for HHV-6B). Induces apoptosis effectively without exerting much genotoxicity.

警告

Toxicity: Carcinogenic / Teratogenic (D)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.

其他说明

Leary, J.J., et al. 2002.Antimicrob. Agents Chemother.46, 762.
Amjad, M., et al. 2001. Microbiol. Immunol.45, 233.
Thust, R., et al. 2000. Cancer Gene Ther.7, 107.
Thust, R., et al. 1996. Antiviral Res.31, 105.
Shaw, T., et al. 1994. Antimicrob. Agents Chemother.38, 719.
Harnden, M.R. 1989. J. Med. Chem.32, 1738.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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